CtaC

• Description: cytochrome-c oxidase (subunit II)
  
  

Gene name	ctaC
Synonyms
Essential	no
Product	cytochrome-c oxidase (subunit II)
Function	respiration
MW, pI	39 kDa, 8.635
Gene length, protein length	1068 bp, 356 aa
Immediate neighbours	ctaB, ctaD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU14890

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 4 ferrocytochrome c + O₂ + 4 H⁺ = 4 ferricytochrome c + 2 H₂O (according to Swiss-Prot)

• Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P24011

• KEGG entry: [3]

• E.C. number: 1.9.3.1

Expression and regulation

• Operon:

• Sigma factor:

• Regulation: repressed by glucose (11-fold) (CcpA) PubMed
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism: CcpA: transcription repression
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed