YxaL

• Description: similar to Ser/Thr kinase
  
  

Gene name	yxaL
Synonyms	yxaK
Essential	no
Product	unknown
Function	unknown
MW, pI	43 kDa, 6.379
Gene length, protein length	1230 bp, 410 aa
Immediate neighbours	yxaM, yxaJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU39940

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YxaL-PcrA

• Localization: secreted (according to Swiss-Prot), extracellular (signal peptide) PubMed

Database entries

• Structure:

• Swiss prot entry: P42111

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yxaJ-yxaL PubMed

• Sigma factor:

• Regulation:
  • repressed by Rok PubMed

• Regulatory mechanism:
  • Rok: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector: pGP392 (N-terminal Strep-tag, purification from B. subtilis, for SPINE, in pGP380), available in Stülke lab

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Voigt et al. (2009) Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis. J Mol Microbiol Biotechnol. 16: 53-68 PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed