Difference between revisions of "L-box"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
The L-box is a [[riboswitch]] that binds lysine and controls gene expression by a termination/ antitermination mechanism.
+
The L-box is a [[riboswitch]] that binds lysine and controls gene expression by a termination/ antitermination mechanism. Upon binding of lysine, the L-box adopts a terminator structure thtus preventing expression of ''[[lysC]]''. In the absence of lysine, the L-box has an antiterminator structure that allows ''[[lysC]]'' expression and thus lysine biosynthesis.
  
 
==Gene controlled by a L-box mechanism==
 
==Gene controlled by a L-box mechanism==
Line 5: Line 5:
 
[[lysC]]
 
[[lysC]]
  
 +
==Reference==
 
<pubmed> 14523230  </pubmed>
 
<pubmed> 14523230  </pubmed>

Revision as of 13:00, 7 June 2009

The L-box is a riboswitch that binds lysine and controls gene expression by a termination/ antitermination mechanism. Upon binding of lysine, the L-box adopts a terminator structure thtus preventing expression of lysC. In the absence of lysine, the L-box has an antiterminator structure that allows lysC expression and thus lysine biosynthesis.

Gene controlled by a L-box mechanism

lysC

Reference

Frank J Grundy, Susan C Lehman, Tina M Henkin
The L box regulon: lysine sensing by leader RNAs of bacterial lysine biosynthesis genes.
Proc Natl Acad Sci U S A: 2003, 100(21);12057-62
[PubMed:14523230] [WorldCat.org] [DOI] (P p)