Difference between revisions of "Hbs"
Line 95: | Line 95: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
+ | ** repressed when no DNA damage is present ([[LexA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16267290 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[LexA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16267290 PubMed] | ||
* '''Additional information:''' mRNA is protected from degradation by [[RnjA]] by initiating ribosomes [http://www.ncbi.nlm.nih.gov/sites/entrez/19210617 PubMed] | * '''Additional information:''' mRNA is protected from degradation by [[RnjA]] by initiating ribosomes [http://www.ncbi.nlm.nih.gov/sites/entrez/19210617 PubMed] |
Revision as of 16:52, 11 June 2009
- Description: non-specific DNA-binding protein Hbsu
Gene name | hbs |
Synonyms | dbpA |
Essential | yes PubMed |
Product | non-specific DNA-binding protein Hbsu |
Function | DNA packaging, function of the signal recognition complex |
MW, pI | 9 kDa, 9.501 |
Gene length, protein length | 276 bp, 92 aa |
Immediate neighbours | mtrA, spoIVA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU22790
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: DbpA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Thr-4 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot), membrane associated PubMed
Database entries
- Structure: 1HUU (Geobacillus stearothermophilus), 1EXE (phage SPO1 transcription factor, 45% identity)
- Swiss prot entry: P42305
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Ciaran Condon, IBPC, Paris, France Homepage
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed