Difference between revisions of "Sandbox"

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* '''Description:''' methyl-accepting chemotaxis protein <br/><br/>
+
* '''Description:''' transcription activator of the hxlA-hxlB operon <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''tlpC''
+
|''hxlR''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yckH ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || methyl-accepting chemotaxis protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || transcription activator 
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of chemotaxis
+
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the ribulose monophosphate pathway
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 61 kDa, 4.929  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 6.358  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1719 bp, 573 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 360 bp, 120 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nucA]]'', ''[[hxlB]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hxlA]]'', ''[[srfAA]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12138&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12141&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
 
|-
 
|-
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:tlpC_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:hxlR_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
Line 43: Line 43:
 
=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tlpC.html]
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/hxlR.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10790]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11184]
  
 
=== Additional information===
 
=== Additional information===
Line 70: Line 70:
 
* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:'''
+
* '''Effectors of protein activity:''' formaldehyde stimulates transcription activation by HxlR
  
 
* '''Interactions:'''
 
* '''Interactions:'''
Line 82: Line 82:
 
* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU03440]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU03470]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
Line 90: Line 90:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''hxlR''
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  

Revision as of 17:51, 21 April 2009

  • Description: transcription activator of the hxlA-hxlB operon

Gene name hxlR
Synonyms yckH
Essential no
Product transcription activator
Function regulation of the ribulose monophosphate pathway
MW, pI 14 kDa, 6.358
Gene length, protein length 360 bp, 120 aa
Immediate neighbours hxlA, srfAA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HxlR context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: formaldehyde stimulates transcription activation by HxlR
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: hxlR
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed