Difference between revisions of "Sandbox"
Line 1: | Line 1: | ||
− | * '''Description:''' | + | * '''Description:''' Modulator of CcpN activity<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
− | |'' | + | |''yqfL'' |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || modulator of [[CcpN]] activity |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || inhibits [[CcpN]] activity |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || | + | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30,4 kDa, 5.78 |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || | + | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 810 bp, 270 amino acids |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqxD]]'', ''[[ccpN]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein''' | ||
|- | |- | ||
− | |colspan="2" | '''Genetic context''' <br/> [[Image: | + | |colspan="2" | '''Genetic context''' <br/> [[Image:yqfL_context.gif]] |
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
Line 29: | Line 29: | ||
__TOC__ | __TOC__ | ||
− | + | <br/><br/> | |
Line 36: | Line 36: | ||
=== Basic information === | === Basic information === | ||
− | * '''Coordinates:''' | + | * '''Coordinates:''' 2603357 - 2604166 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
− | |||
=== Database entries === | === Database entries === | ||
Line 45: | Line 44: | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ccpN-yqfL.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ccpN-yqfL.html] | ||
− | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+ | + | * '''SubtiList entry:'''[http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11659] |
=== Additional information=== | === Additional information=== | ||
Line 53: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' negative effector of [[CcpN]] activity [http://www.ncbi.nlm.nih.gov/sites/entrez/15720552 PubMed] |
− | * '''Protein family:''' | + | * '''Protein family:''' pyruvate, phosphate dikinase regulatory protein family |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
Line 63: | Line 62: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
− | * '''Domains:''' | + | * '''Domains:''' nucleotide binding domain (ATP) (151–158) |
* '''Modification:''' | * '''Modification:''' | ||
Line 69: | Line 68: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
− | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' |
− | |||
− | |||
* '''Interactions:''' | * '''Interactions:''' | ||
Line 81: | Line 78: | ||
* '''Structure:''' | * '''Structure:''' | ||
− | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/ | + | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54470] |
− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU25240] |
+ | |||
+ | * '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.-.- 2.7.-.-] | ||
=== Additional information=== | === Additional information=== | ||
Line 94: | Line 93: | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
− | * '''Regulation:''' | + | * '''Regulation:''' constitutive [http://www.ncbi.nlm.nih.gov/sites/entrez/15720552 PubMed] |
* '''Additional information:''' | * '''Additional information:''' | ||
Line 100: | Line 99: | ||
=Biological materials = | =Biological materials = | ||
− | * '''Mutant:''' | + | * '''Mutant:''' |
* '''Expression vector:''' | * '''Expression vector:''' | ||
Line 108: | Line 107: | ||
* '''GFP fusion:''' | * '''GFP fusion:''' | ||
− | * '''Antibody:''' | + | * '''Antibody:''' |
=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
− | |||
[[Stephane Aymerich |Stephane Aymerich]], Microbiology and Molecular Genetics, INRA Paris-Grignon, France | [[Stephane Aymerich |Stephane Aymerich]], Microbiology and Molecular Genetics, INRA Paris-Grignon, France | ||
− | |||
− | |||
=Your additional remarks= | =Your additional remarks= | ||
=References= | =References= | ||
− | |||
# Servant et al. (2005) CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of ''Bacillus subtilis'' gluconeogenic genes. Mol. Microbiol. 55: 1435-1451. [http://www.ncbi.nlm.nih.gov/sites/entrez/15720552 PubMed] | # Servant et al. (2005) CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of ''Bacillus subtilis'' gluconeogenic genes. Mol. Microbiol. 55: 1435-1451. [http://www.ncbi.nlm.nih.gov/sites/entrez/15720552 PubMed] | ||
− | |||
− | |||
− | |||
− |
Revision as of 18:45, 15 April 2009
- Description: Modulator of CcpN activity
Gene name | yqfL |
Synonyms | |
Essential | no |
Product | modulator of CcpN activity |
Function | inhibits CcpN activity |
MW, pI | 30,4 kDa, 5.78 |
Gene length, protein length | 810 bp, 270 amino acids |
Immediate neighbours | yqxD, ccpN |
Hier soll was neues rein | |
Genetic context ![]() This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Coordinates: 2603357 - 2604166
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry:[2]
Additional information
The protein
Basic information/ Evolution
- Protein family: pyruvate, phosphate dikinase regulatory protein family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: nucleotide binding domain (ATP) (151–158)
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: 2.7.-.-
Additional information
Expression and regulation
- Regulation: constitutive PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- Antibody:
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
Your additional remarks
References
- Servant et al. (2005) CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of Bacillus subtilis gluconeogenic genes. Mol. Microbiol. 55: 1435-1451. PubMed