Difference between revisions of "DnaB"

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* '''Description:''' write here <br/><br/>
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* '''Description:''' initiation of chromosome replication/ membrane attachment protein <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || membrane attachment protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || initiation of chromosome replication/ membrane attachment protein
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of chromosome replication
+
|style="background:#ABCDEF;" align="center"|'''Function''' || DNA replication
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.278   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.278   

Revision as of 15:02, 16 March 2009

  • Description: initiation of chromosome replication/ membrane attachment protein

Gene name dnaB
Synonyms
Essential yes PubMed
Product initiation of chromosome replication/ membrane attachment protein
Function DNA replication
MW, pI 54 kDa, 5.278
Gene length, protein length 1416 bp, 472 aa
Immediate neighbours dnaI, ytcG
Gene sequence (+200bp) Protein sequence
Genetic context
DnaB context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: forms foci, close to oriC PubMed

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Haroniti et al. (2004) The clamp-loader-helicase interaction in Bacillus. Atomic force microscopy reveals the structural organisation of the DnaB-tau complex in Bacillus.J. Mol. Biol. 336: 381-393. PubMed
  2. Imai et al. (2000) Subcellular localization of Dna-initiation proteins of Bacillus subtilis: evidence that chromosome replication begins at either edge of the nucleoids. Mol. Microbiol. 36: 1037-1048. PubMed