PghL

• Description: phage-derived gamma polyglutamic acid hydrolase, sporulation protein
  
  

Gene name	pghL
Synonyms	yndL
Essential	no
Product	phage-derived gamma polyglutamic acid hydrolase
Function	polyglutamic acid degradation
Gene expression levels in SubtiExpress: pghL
MW, pI	28 kDa, 6.92
Gene length, protein length	756 bp, 252 aa
Immediate neighbours	surA, yndM
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

capsule biosynthesis and degradation, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU17820

Database entries

• BsubCyc: BSU17820

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • hyhrolysis of polyglutamic acid PubMed

• Protein family: UPF0714 family (according to Swiss-Prot)

• Paralogous protein(s): PghB, PghC, PghZ

Extended information on the protein

• Kinetic information:

• Domains: DUF867 [3], gamma-PGA hydrolase domain PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU17820

• Structure:

• UniProt: O31815

• KEGG entry: [4]

• E.C. number:

Expression and regulation

• Operon: pghL PubMed

• Expression browser: pghL PubMed

• Sigma factor: SigK PubMed

• Regulation: expressed during sporulation in the mother cellPubMed

• Regulatory mechanism:

• Additional information:
  • An antisense RNA, surA, is predicted for pghL PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: