Difference between revisions of "RhaEW"

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m (Jstuelk moved page YuxG to RhaEW)
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* '''Description:''' similar to sorbitol-6-phosphate 2-dehydrogenase <br/><br/>
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* '''Description:''' bifunctional-rhamnulose-phosphate aldolase/L-lactate dehydrogenase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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|style="background:#ABCDEF;" align="center"| '''Product''' || bifunctional-rhamnulose-phosphate aldolase/L-lactate dehydrogenase
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|style="background:#ABCDEF;" align="center"|'''Function''' || utilizatio of rhamnose and rhamnogalacturonan (pectin)
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31220 yuxG]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31220 yuxG]
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2067 bp, 689 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2067 bp, 689 aa  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yulB]]'', ''[[tlpB]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rhaR]]'', ''[[tlpB]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31220 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31220 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31220 DNA_with_flanks]
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31220 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31220 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31220 DNA_with_flanks]
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<br/><br/><br/><br/>
 
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<br/><br/><br/><br/>
 
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<br/><br/><br/><br/>
 
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<br/><br/>
 
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}}
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{{SubtiWiki category|[[utilization of specific carbon sources]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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=== Additional information===
 
=== Additional information===
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−
 
−
 
  
 
=The protein=
 
=The protein=
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
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* '''Catalyzed reaction/ biological activity:'''  
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* '''Catalyzed reaction/ biological activity:''' rhamnulose-1-phosphate --> dihydroxyacetone-phosphate + L-lactate {{PubMed|24391637}}
  
 
* '''Protein family:''' short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
 
* '''Protein family:''' short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
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* '''Domains:'''  
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* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
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* '''Cofactor(s):'''
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* '''[[Cofactors]]:''' NAD<sup>+</sup> {{PubMed|24391637}}
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
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* '''Interactions:'''
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* '''[[SubtInteract|Interactions]]:'''  
  
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* '''Localization:'''
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* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
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=Expression and regulation=
 
=Expression and regulation=
  
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* '''Operon:'''  
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* '''Operon:''' ''[[rhaEW]]-[[rhaR]]-[[rhaB]]-[[rhaM]]-[[rhaA]]'' {{PubMed|22383849}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yuxG_3201860_3203929_-1 yuxG] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yuxG_3201860_3203929_-1 yuxG] {{PubMed|22383849}}
  
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* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=References=
 
=References=
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<pubmed>24391637 </pubmed>
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<pubmed>24391637 22383849</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 14:46, 7 June 2014

  • Description: bifunctional-rhamnulose-phosphate aldolase/L-lactate dehydrogenase

Gene name yuxG
Synonyms yulA
Essential no
Product bifunctional-rhamnulose-phosphate aldolase/L-lactate dehydrogenase
Function utilizatio of rhamnose and rhamnogalacturonan (pectin)
Gene expression levels in SubtiExpress: yuxG
MW, pI 75 kDa, 5.779
Gene length, protein length 2067 bp, 689 aa
Immediate neighbours rhaR, tlpB
Sequences Protein DNA DNA_with_flanks
Genetic context
YuxG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YuxG expression.png















Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU31220

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: rhamnulose-1-phosphate --> dihydroxyacetone-phosphate + L-lactate PubMed
  • Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Irina A Rodionova, Xiaoqing Li, Vera Thiel, Sergey Stolyar, Krista Stanton, James K Fredrickson, Donald A Bryant, Andrei L Osterman, Aaron A Best, Dmitry A Rodionov
Comparative genomics and functional analysis of rhamnose catabolic pathways and regulons in bacteria.
Front Microbiol: 2013, 4;407
[PubMed:24391637] [WorldCat.org] [DOI] (P e)

Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849] [WorldCat.org] [DOI] (I p)

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