tig
168
trigger factor (prolyl isomerase)
Locus
BSU_28230
Molecular weight
47.00 kDa
Isoelectric point
4
Function
protein folding
Product
trigger factor (prolyl isomerase)
Essential
no
E.C.
5.2.1.8
Synonyms
tig, yzzH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0544 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
The protein
Catalyzed reaction/ biological activity
[protein]-peptidylproline (=180) --> [protein]-peptidylproline (=0) (according to UniProt)
Protein family
FKBP-type PPIase family (single member, according to UniProt)
PPIase FKBP-type domain (aa 163-248) (according to UniProt)
Structure
2VRH (PDB) (the E. coli trigger factor) PubMed
Modification
Additional information
subject to Clp-dependent proteolysis upon glucose starvation PubMed
belongs to the 100 most abundant proteins PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
Regulatory mechanism
stringent response: negative regulation, in stringent response
Biological materials
Mutant
References
Reviews
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Original Publications
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Time of last update: 2025-02-24 19:14:15
Author of last update: Jstuelk