Difference between revisions of "SpsI"
| Line 42: | Line 42: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[GerE regulon]]}}, | ||
{{SubtiWiki regulon|[[SigK regulon]]}} | {{SubtiWiki regulon|[[SigK regulon]]}} | ||
| Line 107: | Line 108: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spsI_3885239_3885979_-1 spsI] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spsI_3885239_3885979_-1 spsI] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigK]] {{PubMed|15383836}} | + | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15383836}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed late during sporulation in the mother cell ([[SigK]]) {{PubMed|15383836}} | + | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|25239894,15383836}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[GerE]]: transcription activation {{PubMed|25239894,15383836}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 136: | Line 138: | ||
=References= | =References= | ||
| − | <pubmed>9353933 15383836 12884008 21821766 22960854</pubmed> | + | <pubmed>9353933 15383836 12884008 21821766 22960854 25239894</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:01, 23 September 2014
- Description: glucose-1-phosphate thymidylyltransferase, spore coat polysaccharide synthesis
| Gene name | spsI |
| Synonyms | ipa-71d |
| Essential | no |
| Product | glucose-1-phosphate thymidylyltransferase |
| Function | rhamnose biosynthesis, spore coat polysaccharide synthesis |
| Gene expression levels in SubtiExpress: spsI | |
| MW, pI | 27 kDa, 5.385 |
| Gene length, protein length | 738 bp, 246 aa |
| Immediate neighbours | spsJ, spsG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU37840
Phenotypes of a mutant
Database entries
- BsubCyc: BSU37840
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- alpha-D-glucose-1-phosphate + dTTP --> dTDP-glucose PubMed
- Protein family: glucose-1-phosphate thymidylyltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU37840
- Structure:
- UniProt: P39629
- KEGG entry: [3]
- E.C. number: 2.7.7.24
Additional information
Expression and regulation
- Additional information:
- the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
