Difference between revisions of "LutR"

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* '''Description:''' repressor of the ''[[lutA]]-[[lutB]]-[[lutC]]'' operon <br/><br/>
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* '''Description:''' transcriptional repressor ([[GntR family]]) of the ''[[lutA]]-[[lutB]]-[[lutC]]'' operon <br/><br/>
  
 
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= [[Categories]] containing this gene/protein =
 
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=

Revision as of 17:51, 11 June 2014

Gene name lutR
Synonyms yvfI
Essential no
Product transcriptional repressor, (GntR family)
Function control of lactate utilization
Gene expression levels in SubtiExpress: lutR
Metabolic function and regulation of this protein in SubtiPathways:
lutR
MW, pI 19 kDa, 4.845
Gene length, protein length 525 bp, 175 aa
Immediate neighbours lacR, lutP
Sequences Protein DNA DNA_with_flanks
Genetic context
YvfI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LutR expression.png















Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

The LutR regulon:

The gene

Basic information

  • Locus tag: BSU34180

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcriptional repressor of the lutA-lutB-lutC operon PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: lactate acts as molecular inducer PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: TEK1 lutR::Tn10::spc PubMed
  • Expression vector: pQE60-lutR (His-tag) PubMed
  • lacZ fusion: TEK7 lutR::lacZ::erm PubMed
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Ayten Katatas, Istanbul Technical University, Istanbul, Turkey [3]

Your additional remarks

References

Additional publications: PubMed