SpoVID

• Description: spore coat morphogenetic protein, promotes encasement of the spore
  
  

Gene name	spoVID
Synonyms
Essential	no
Product	spore coat morphogenetic protein
Function	spore coat assembly
Gene expression levels in SubtiExpress: spoVID
Interactions involving this protein in SubtInteract: SpoVID
MW, pI	64 kDa, 3.999
Gene length, protein length	1725 bp, 575 aa
Immediate neighbours	ysxE, hemL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU28110

Database entries

• BsubCyc: BSU28110

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • SpoIVA-SpoVID PubMed
  • SpoVID-SafA PubMed
  • SpoIVA-SpoVM-SpoVID PubMed
  • SpoVID-CotE PubMed

• Localization:
  • spore coat (basement), localization depends on SpoIVA PubMed

Database entries

• BsubCyc: BSU28110

• Structure:

• UniProt: P37963

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVID-ysxE PubMed

• Expression browser: spoVID PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed
  • repressed by casamino acids PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A639 ( spoVID::erm), PubMed, available at BGSC
  • 1S127 ( spoVID::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Adriano Henriques, Lisbon, Portugal homepage
• Charles Moran, Emory University, NC, USA homepage

References

Reviews

Peter T McKenney, Adam Driks, Patrick Eichenberger
The Bacillus subtilis endospore: assembly and functions of the multilayered coat.
Nat Rev Microbiol: 2013, 11(1);33-44
[PubMed:23202530] [WorldCat.org] [DOI] (I p)