RodZ

• Description: required for cell shape determination
  
  

Gene name	rodZ
Synonyms	ymfM
Essential	may be essential PubMed
Product	morphogenic protein
Function	required for cell shape determination
Gene expression levels in SubtiExpress: rodZ
Interactions involving this protein in SubtInteract: RodZ
MW, pI	23 kDa, 4.679
Gene length, protein length	639 bp, 213 aa
Immediate neighbours	ymfK/2, pgsA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell shape, membrane proteins

The gene

Basic information

• Locus tag: BSU16910

Phenotypes of a mutant

• may be essential PubMed
• depletion results in the formation of shorter and rounder cells PubMed

Database entries

• BsubCyc: BSU16910

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • part of the cell wall biosynthetic complex PubMed
  • RodZ-MreD PubMed
  • RodZ-MreB PubMed
  • RodZ-MreBH PubMed
  • RodZ-Mbl PubMed

• Localization:
  • membrane protein (according to Swiss Prot)

Database entries

• BsubCyc: BSU16910

• Structure:

• UniProt: O31771

• KEGG entry: [2]

• E.C. number:

Additional information

• overexpression results in growth inhibition in minimal medium (in the absence of Mg2+ ) PubMed
• RodZ is destabilized in a mreB mutant PubMed

Expression and regulation

• Operon:

• Expression browser: rodZ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 73 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 497 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Adriano Henriques, Lisbon, Portugal homepage