EcsA

• Description: ABC transporter (ATP-binding protein), mutation affects proteolysis by RasP (no processing of RsiW and FtsL)
  
  

Gene name	ecsA
Synonyms	prsT, ecs-26, yhaD
Essential	no
Product	ABC transporter (ATP-binding protein)
Function	regulation of the secretion apparatus and of intra-membrane proteolysis
Gene expression levels in SubtiExpress: ecsA
Interactions involving this protein in SubtInteract: EcsA
MW, pI	27 kDa, 5.635
Gene length, protein length	741 bp, 247 aa
Immediate neighbours	hit, ecsB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, protein secretion, sigma factors and their control, membrane proteins

The gene

Basic information

• Locus tag: BSU10040

Phenotypes of a mutant

no processing of RsiW and FtsL PubMed

Database entries

• BsubCyc: BSU10040

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: EcsA-EcsB PubMed

• Localization: membrane associated (via EcsB) PubMed

Database entries

• BsubCyc: BSU10040

• Structure:

• UniProt: P55339

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ecsA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 43 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 155 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: