Difference between revisions of "SunA"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU21480&redirect=T BSU21480] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sunA.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sunA.html] | ||
| Line 93: | Line 94: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU21480&redirect=T BSU21480] | ||
* '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=2MIJ 2MIJ] {{PubMed|24405370}} | * '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=2MIJ 2MIJ] {{PubMed|24405370}} | ||
Revision as of 14:59, 2 April 2014
- Description: sublancin 168 lantibiotic antimicrobial precursor peptide
| Gene name | sunA |
| Synonyms | yolG |
| Essential | no |
| Product | sublancin 168 lantibiotic antimicrobial precursor peptide |
| Function | antimicrobial peptide |
| Gene expression levels in SubtiExpress: sunA | |
| MW, pI | 5 kDa, 7.963 |
| Gene length, protein length | 168 bp, 56 aa |
| Immediate neighbours | sunT, sunI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, toxins, antitoxins and immunity against toxins, SP-beta prophage, membrane proteins
This gene is a member of the following regulons
Abh regulon, AbrB regulon, Rok regulon, YvrHb regulon
The gene
Basic information
- Locus tag: BSU21480
Phenotypes of a mutant
Database entries
- BsubCyc: BSU21480
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: IPP isomerase type 2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification: contains a glucose attached to a cysteine residue, glycosylation is essential for its antimicrobial activity PubMed
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU21480
- UniProt: P68577
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: sunA PubMed
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- GP1563 (aphA3), available in Jörg Stülke's lab
- GP1565 (sunA-sunI, aphA3), available in Jörg Stülke's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
