SigI

• Description: RNA polymerase sigma factor SigI
  
  

Gene name	sigI
Synonyms	ykoZ
Essential	no
Product	RNA polymerase sigma factor SigI
Function	control of a class of heat shock genes
Gene expression levels in SubtiExpress: sigI
Interactions involving this protein in SubtInteract: SigI
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	29 kDa, 8.306
Gene length, protein length	753 bp, 251 aa
Immediate neighbours	ykoY, rsgI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription, sigma factors and their control, heat shock proteins

This gene is a member of the following regulons

SigI regulon, WalR regulon

The gene

Basic information

• Locus tag: BSU13450

Phenotypes of a mutant

• temperature-sensitive growth on agar plates PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • RsgI-SigI, the interaction inhibits SigI activity PubMed
  • SigI-RpoB-RpoC

• Localization:

Database entries

• Structure:

• UniProt: O31654

• KEGG entry: [3]

• E.C. number:

Additional information

overexpression of SigI suppresses mreB mreBH mbl mutants PubMed

Expression and regulation

• Operon: sigI-rsgI PubMed

• Expression browser: sigI PubMed

• Sigma factor: SigI PubMed

• Regulation:
  • induced at high temperature (SigI, WalR) PubMed

• Regulatory mechanism:
  • WalR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: