Difference between revisions of "SigI"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigI regulon]]}} | + | {{SubtiWiki regulon|[[SigI regulon]]}}, |
| + | {{SubtiWiki regulon|[[WalR regulon]]}} | ||
=The [[SigI regulon]]: ''[[bcrC]]'', ''[[gsiB]]'', ''[[lytE]]'', ''[[mreBH]]'', ''[[sigI]]-[[rsgI]]''= | =The [[SigI regulon]]: ''[[bcrC]]'', ''[[gsiB]]'', ''[[lytE]]'', ''[[mreBH]]'', ''[[sigI]]-[[rsgI]]''= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Sigma factor:''' [[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | * '''Sigma factor:''' [[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | ||
| − | * '''Regulation:''' induced | + | * '''Regulation:''' |
| + | ** induced at high temperature ([[SigI]], [[WalR]]) {{PubMed|24125693,17185538}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[WalR]]: transcription activation {{PubMed|24125693}} | ||
| + | |||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed>19114499,17185538,11157964 18156261, 21541672 </pubmed> | + | <pubmed>19114499,17185538,11157964 18156261, 21541672 24125693</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:38, 23 December 2013
- Description: RNA polymerase sigma factor SigI
| Gene name | sigI |
| Synonyms | ykoZ |
| Essential | no |
| Product | RNA polymerase sigma factor SigI |
| Function | control of a class of heat shock genes |
| Gene expression levels in SubtiExpress: sigI | |
| Interactions involving this protein in SubtInteract: SigI | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 29 kDa, 8.306 |
| Gene length, protein length | 753 bp, 251 aa |
| Immediate neighbours | ykoY, rsgI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transcription, sigma factors and their control, heat shock proteins
This gene is a member of the following regulons
The SigI regulon: bcrC, gsiB, lytE, mreBH, sigI-rsgI
The gene
Basic information
- Locus tag: BSU13450
Phenotypes of a mutant
- temperature-sensitive growth on agar plates PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31654
- KEGG entry: [3]
- E.C. number:
Additional information
overexpression of SigI suppresses mreB mreBH mbl mutants PubMed
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
