Difference between revisions of "NprE"

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(Categories containing this gene/protein)
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
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* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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<pubmed>20735481 </pubmed>
 
<pubmed>20735481 </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>1906467,18957862,20817675 </pubmed>
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<pubmed>1906467,18957862,20817675 24115457 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:00, 20 February 2014

  • Description: extracellular neutral protease B

Gene name nprE
Synonyms
Essential no
Product extracellular neutral protease B
Function degradation of proteins
Gene expression levels in SubtiExpress: nprE
MW, pI 56 kDa, 7.481
Gene length, protein length 1563 bp, 521 aa
Immediate neighbours yktD, ylaA
Sequences Protein DNA DNA_with_flanks
Genetic context
NprE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NprE expression.png















Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, proteolysis

This gene is a member of the following regulons

AbrB regulon, ScoC regulon

The gene

Basic information

  • Locus tag: BSU14700

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Similar, but not identical, to that of thermolysin (according to Swiss-Prot)
  • Protein family: peptidase M4 family (according to Swiss-Prot)
  • Paralogous protein(s): NprB

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 1NPC (of Bacillus cereus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: nprE (according to DBTBS)
  • Regulation:
    • repressed during exponential growth (ScoC) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications