Difference between revisions of "CotS"
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| − | * '''Description:''' spore coat protein <br/><br/> | + | * '''Description:''' outer spore coat protein <br/><br/> |
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigK regulon]]}} | + | {{SubtiWiki regulon|[[SigK regulon]]}}, |
| + | {{SubtiWiki regulon|[[GerE regulon]]}} | ||
| + | |||
=The gene= | =The gene= | ||
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| − | ** spore | + | ** outer spore coat, localization depends on [[CotE]] {{PubMed|22171814}} |
=== Database entries === | === Database entries === | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed late during sporulation in the mother cell ([[SigK]]) {{PubMed|15699190,9603889}} | + | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15383836,15699190,9603889}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[GerE]]: transcription activation {{PubMed|15383836}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed>11737650,7545510,9603889,14702409,10234840,15699190,, </pubmed> | + | <pubmed>11737650,7545510,9603889,14702409,10234840,15699190,22171814, 15383836</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:47, 13 August 2013
- Description: outer spore coat protein
| Gene name | cotS |
| Synonyms | |
| Essential | no |
| Product | spore coat protein |
| Function | resistance of the spore |
| Gene expression levels in SubtiExpress: cotS | |
| MW, pI | 40 kDa, 6.641 |
| Gene length, protein length | 1053 bp, 351 aa |
| Immediate neighbours | ytxO, cotSA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30900
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: cotS family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P46914
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
Ritsuko Kuwana, Hiromi Ikejiri, Satoko Yamamura, Hiromu Takamatsu, Kazuhito Watabe
Functional relationship between SpoVIF and GerE in gene regulation during sporulation of Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 1);163-170
[PubMed:14702409]
[WorldCat.org]
[DOI]
(P p)
S Little, A Driks
Functional analysis of the Bacillus subtilis morphogenetic spore coat protein CotE.
Mol Microbiol: 2001, 42(4);1107-20
[PubMed:11737650]
[WorldCat.org]
[DOI]
(P p)
H Takamatsu, T Kodama, K Watabe
Assembly of the CotSA coat protein into spores requires CotS in Bacillus subtilis.
FEMS Microbiol Lett: 1999, 174(1);201-6
[PubMed:10234840]
[WorldCat.org]
[DOI]
(P p)
H Takamatsu, Y Chikahiro, T Kodama, H Koide, S Kozuka, K Tochikubo, K Watabe
A spore coat protein, CotS, of Bacillus subtilis is synthesized under the regulation of sigmaK and GerE during development and is located in the inner coat layer of spores.
J Bacteriol: 1998, 180(11);2968-74
[PubMed:9603889]
[WorldCat.org]
[DOI]
(P p)
Akiko Abe, Hidekatsu Koide, Takeyuki Kohno, Kazuhito Watabe
A Bacillus subtilis spore coat polypeptide gene, cotS.
Microbiology (Reading): 1995, 141 ( Pt 6);1433-1442
[PubMed:7545510]
[WorldCat.org]
[DOI]
(P p)
