hemX

hemX
168

negative effector of the concentration of HemA

Locus
BSU_28160
Molecular weight
31.89 kDa
Isoelectric point
9.28
Protein length
276 aaSequenceBlast
Gene length
831 bpSequenceBlast
Function
heme biosynthesis
Product
regulatory protein, protease?
Essential
no
Synonyms
hemX
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0755 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,876,928  2,877,758
The protein
Structure
P16645 (AlphaFold)
Expression and Regulation
Operons
Genes
hemA-hemX-hemC-hemD-hemB-hemL
Description
PubMed
Regulation
induced by hydrogen peroxide (PerR) PubMed
Regulatory mechanism
PerR: repression, PubMed, in perR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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hemA→hemL

2025-02-27 17:14:02

ghost

103

64840dd729762069005c4bd541ed0ddec6e74ace

168BC8B91CBFE3EA050DA8A9187C8C67D6BBE4F9

Biological materials
Mutant
BKE28160 (hemX::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCAGTATCAATCATTC,  downstream forward: _UP4_TAAACGATGTCCCAAGCAGA
BKK28160 (hemX::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCAGTATCAATCATTC,  downstream forward: _UP4_TAAACGATGTCCCAAGCAGA
References
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88616BA1E853E11BE0CB18F06287CA4C68143148

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Time of last update: 2025-03-03 00:11:23

Author of last update: Bzhu