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− | * '''Description:''' formamidopyrimidine-DNA glycosidase <br/><br/>
| + | 1305064653 http://manuals8j0k.pp.ua/ http://manuals8j0k.pp.ua/tctf2.html http://manuals8j0k.pp.ua/nxy1.html http://manuali4q9t.pp.ua/ http://manuali4q9t.pp.ua/wiwtdh2.html http://manuali4q9t.pp.ua/vmlrtk1.html http://rukovodstxip.pp.ua/ http://rukovodstxip.pp.ua/ddogmi2.html http://rukovodstxip.pp.ua/selfy1.html http://manualsg7d.pp.ua/ http://manualsg7d.pp.ua/xom2.html http://manualsg7d.pp.ua/aarrq1.html http://instructionsrufh.pp.ua/ http://instructionsrufh.pp.ua/qpa2.html http://instructionsrufh.pp.ua/tauc1.html http://manualix13.pp.ua/ http://manualix13.pp.ua/kka1.html http://manualix13.pp.ua/paes2.html http://manualiy30.pp.ua/ http://manualiy30.pp.ua/ptie2.html http://manualiy30.pp.ua/htn1.html |
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− | {| align="right" border="1" cellpadding="2"
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− | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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− | |''mutM''
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− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytaE ''
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− | |-
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− | |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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− | |style="background:#ABCDEF;" align="center"| '''Product''' || formamidopyrimidine-DNA glycosidase
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− | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair
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− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29080 mutM]
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− | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 8.889
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− | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 834 bp, 278 aa
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− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytaF]]'', ''[[polA]]''
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− | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29080 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29080 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29080 Advanced_DNA]
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− | |colspan="2" | '''Genetic context''' <br/> [[Image:mutM_context.gif]]
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− | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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− | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mutM_2972329_2973159_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:mutM_expression.png|500px]]
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− | |}
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− | __TOC__
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− | <br/><br/><br/><br/>
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− | <br/><br/><br/><br/>
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− | <br/><br/><br/><br/>
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− | <br/><br/><br/><br/>
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− | <br/><br/><br/><br/>
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− | <br/><br/>
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− | = [[Categories]] containing this gene/protein =
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− | {{SubtiWiki category|[[DNA repair/ recombination]]}}
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− | | |
− | = This gene is a member of the following [[regulons]] =
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− | | |
− | | |
− | =The gene=
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− | | |
− | === Basic information ===
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− | * '''Locus tag:''' BSU29080
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− | | |
− | ===Phenotypes of a mutant ===
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− | === Database entries ===
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− | * '''DBTBS entry:''' no entry
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− | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12628]
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− | === Additional information===
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− | | |
− | =The protein=
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− | | |
− | === Basic information/ Evolution ===
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− | * '''Catalyzed reaction/ biological activity:''' Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine (according to Swiss-Prot)
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− | * '''Protein family:''' FPG family (according to Swiss-Prot)
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− | * '''Paralogous protein(s):'''
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− | === Extended information on the protein ===
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− | * '''Kinetic information:'''
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− | * '''Domains:'''
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− | * '''Modification:'''
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− | * '''Cofactor(s):'''
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− | * '''Effectors of protein activity:'''
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− | * '''[[SubtInteract|Interactions]]:'''
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− | * '''[[Localization]]:'''
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− | ** cytoplasm (according to Swiss-Prot)
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− | | |
− | === Database entries ===
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− | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2F5S 2F5S] (complex with oxoG:C, Geobacillus stearothermophilus)
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− | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34403 O34403]
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− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU29080]
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− | * '''E.C. number:''' [http://www.expasy.org/enzyme/3.2.2.23 3.2.2.23]
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− | === Additional information===
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− | =Expression and regulation=
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− | * '''Operon:'''
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− | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mutM_2972329_2973159_-1 mutM] {{PubMed|22383849}}
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− | * '''Sigma factor:'''
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− | * '''Regulation:'''
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− | * '''Regulatory mechanism:'''
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− | * '''Additional information:'''
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− | =Biological materials =
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− | * '''Mutant:'''
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− | * '''Expression vector:'''
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− | * '''lacZ fusion:'''
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− | * '''GFP fusion:'''
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− | * '''two-hybrid system:'''
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− | * '''Antibody:'''
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− | =Labs working on this gene/protein=
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− | =Your additional remarks=
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− | =References=
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− | <pubmed> 19011023 19889642 </pubmed>
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− | [[Category:Protein-coding genes]]
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