Difference between revisions of "YjbH"

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|style="background:#ABCDEF;" align="center"|'''Function''' || stimulation of [[Spx]] degradation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || stimulation of [[Spx]] degradation
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU11550 yjbH]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11550 yjbH]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/YjbH YjbH]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/YjbH YjbH]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yizD]]'', ''[[yjbI]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yizD]]'', ''[[yjbI]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13012&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11550 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11550 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11550 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yjbH_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yjbH_context.gif]]

Revision as of 12:33, 13 May 2013

  • Description: adaptor protein for ClpX-ClpP-catalyzed Spx degradation, confers resistance against nitrosating agents

Gene name yjbH
Synonyms
Essential no
Product adaptor protein
Function stimulation of Spx degradation
Gene expression levels in SubtiExpress: yjbH
Interactions involving this protein in SubtInteract: YjbH
MW, pI 31 kDa, 5.206
Gene length, protein length 825 bp, 275 aa
Immediate neighbours yizD, yjbI
Sequences Protein DNA Advanced_DNA
Genetic context
YjbH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YjbH expression.png















Categories containing this gene/protein

proteolysis, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11550

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: adaptor protein for ClpX-ClpP-catalyzed Spx degradation PubMed
  • Protein family: UPF0413 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):contains Zn atoms (coordinated by the N-terminal His-rich region) PubMed
  • Effectors of protein activity:
    • Zn atom is released upon treatment with strong oxidants PubMed
    • interaction with YirB inhibits the formation of a complex with Spx PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Peter Zuber, Oregon Health and Science University, USA Homepage

Claes von Wachenfeldt, Lund University, Sweden Homepage

Your additional remarks

References

Reviews

Additional reviews: PubMed

Aurelia Battesti, Susan Gottesman
Roles of adaptor proteins in regulation of bacterial proteolysis.
Curr Opin Microbiol: 2013, 16(2);140-7
[PubMed:23375660] [WorldCat.org] [DOI] (I p)

Original Publications

Additional publications: PubMed

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