Difference between revisions of "SunA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || antimicrobial peptide | |style="background:#ABCDEF;" align="center"|'''Function''' || antimicrobial peptide | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21480 sunA] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 5 kDa, 7.963 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 5 kDa, 7.963 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sunT]]'', ''[[sunI]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sunT]]'', ''[[sunI]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU21480 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU21480 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU21480 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:sunA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:sunA_context.gif]] | ||
Revision as of 13:05, 13 May 2013
- Description: sublancin 168 lantibiotic antimicrobial precursor peptide
| Gene name | sunA |
| Synonyms | yolG |
| Essential | no |
| Product | sublancin 168 lantibiotic antimicrobial precursor peptide |
| Function | antimicrobial peptide |
| Gene expression levels in SubtiExpress: sunA | |
| MW, pI | 5 kDa, 7.963 |
| Gene length, protein length | 168 bp, 56 aa |
| Immediate neighbours | sunT, sunI |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, toxins, antitoxins and immunity against toxins, SP-beta prophage, membrane proteins
This gene is a member of the following regulons
Abh regulon, AbrB regulon, Rok regulon, YvrHb regulon
The gene
Basic information
- Locus tag: BSU21480
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: IPP isomerase type 2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: contains a glucose attached to a cysteine residue, glycosylation is essential for its antimicrobial activity PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P68577
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: sunA PubMed
- Sigma factor:
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
