Difference between revisions of "UgtP"
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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of glycolipids and anchoring of lipoteichoic <br/>acid, inhibition of [[FtsZ]] assembly | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of glycolipids and anchoring of lipoteichoic <br/>acid, inhibition of [[FtsZ]] assembly | ||
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21920 ugtP] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/UgtP UgtP] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/UgtP UgtP] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[metA]]'', ''[[cspD]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[metA]]'', ''[[cspD]]'' | ||
|- | |- | ||
− | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU21920 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU21920 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU21920 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ugtP_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ugtP_context.gif]] |
Revision as of 13:06, 13 May 2013
- Description: UDP-glucose diacylglycerol glucosyltransferase, growth-rate dependent inhibitor of cell division
Gene name | ugtP |
Synonyms | ypfP |
Essential | no |
Product | UDP-glucose diacylglycerol glucosyltransferase |
Function | synthesis of glycolipids and anchoring of lipoteichoic acid, inhibition of FtsZ assembly |
Gene expression levels in SubtiExpress: ugtP | |
Interactions involving this protein in SubtInteract: UgtP | |
Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
MW, pI | 43 kDa, 8.398 |
Gene length, protein length | 1146 bp, 382 aa |
Immediate neighbours | metA, cspD |
Sequences | Protein DNA Advanced_DNA |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell division, lipid metabolism/ other, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU21920
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- UDP-glucose + 1,2-diacylglycerol = UDP + 1,2-diacyl-3-(O-beta-D-glucopyranosyl)-sn-glycerol (according to Swiss-Prot)
- the interaction with FtsZ results in inhibition of cell division and an increase of cell size PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- membrane-bound protein, self-assembles into tightly wound spirals in vitro PubMed
- under nutrient rich conditions (increased concentration of UDP-Glc): throughout the cell, concentrated at the cell poles and/or the cytokinetic ring, interaction with FtsZ PubMed
- under nutrient poor conditions: forms punctate foci (oligomers), no interaction with FtsZ PubMed
Database entries
- Structure:
- UniProt: P54166
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
Additional publications: PubMed