SspA

• Description: small acid-soluble spore protein (major alpha-type SASP)
  
  

Gene name	sspA
Synonyms
Essential	no
Product	small acid-soluble spore protein (major alpha-type SASP)
Function	protection of spore DNA
Gene expression levels in SubtiExpress: sspA
MW, pI	6 kDa, 4.731
Gene length, protein length	207 bp, 69 aa
Immediate neighbours	ytcI, thiI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU29570

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: alpha/beta-type SASP family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2BZ0 (82% identity, 89% similarity)

• UniProt: P04831

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sspA PubMed

• Expression browser: sspA PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed late during sporulation in the forespore (SigG, SpoVT) PubMed

• Regulatory mechanism:
  • SpoVT: transcription activation PubMed

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:
  • 1S109 (no resistance), available at BGSC
  • 1S111 (no resistance), PubMed, available at BGSC
  • 1S112 (no resistance), PubMed, available at BGSC
  • 1S113 (no resistance), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: