Difference between revisions of "HxlA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || ribulose monophosphate pathway for formaldehyde fixation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || ribulose monophosphate pathway for formaldehyde fixation
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03460 hxlA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03460 hxlA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 4.564   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 4.564   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hxlB]]'', ''[[hxlR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hxlB]]'', ''[[hxlR]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12140&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03460 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03460 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03460 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:hxlA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:hxlA_context.gif]]

Revision as of 12:07, 13 May 2013

  • Description: 3-hexulose-6-phosphate synthase

Gene name hxlA
Synonyms yckG
Essential no
Product 3-hexulose-6-phosphate synthase
Function ribulose monophosphate pathway for formaldehyde fixation
Gene expression levels in SubtiExpress: hxlA
MW, pI 22 kDa, 4.564
Gene length, protein length 630 bp, 210 aa
Immediate neighbours hxlB, hxlR
Sequences Protein DNA Advanced_DNA
Genetic context
HxlA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HxlA expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

HxlR regulon

The gene

Basic information

  • Locus tag: BSU03460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde (according to Swiss-Prot)
  • Protein family: HPS subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: induction by formaldehyde (HxlR) PubMed
  • Regulatory mechanism: transcription activation by HxlR PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References