Difference between revisions of "TrmB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification | |style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29900 trmB] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 6.351 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 6.351 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytnP]]'', ''[[ytzH]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytnP]]'', ''[[ytzH]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29900 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29900 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29900 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ytmQ_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ytmQ_context.gif]] | ||
Revision as of 13:38, 13 May 2013
- Description: tRNA (m7G46) methyltransferase
| Gene name | trmB |
| Synonyms | ytmQ |
| Essential | no |
| Product | tRNA (m7G46) methyltransferase |
| Function | tRNA modification |
| Gene expression levels in SubtiExpress: trmB | |
| MW, pI | 24 kDa, 6.351 |
| Gene length, protein length | 639 bp, 213 aa |
| Immediate neighbours | ytnP, ytzH |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29900
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(7)-methylguanine (according to Swiss-Prot)
- Protein family: TrmB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2FCA
- UniProt: O34522
- KEGG entry: [3]
- E.C. number: 2.1.1.33
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ingrid Zegers, Daniel Gigot, Françoise van Vliet, Catherine Tricot, Stéphane Aymerich, Janusz M Bujnicki, Jan Kosinski, Louis Droogmans
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Nucleic Acids Res: 2006, 34(6);1925-34
[PubMed:16600901]
[WorldCat.org]
[DOI]
(I e)
Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221]
[WorldCat.org]
[DOI]
(P p)
