Difference between revisions of "Rok"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of genetic competence | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of genetic competence | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14240 rok] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykuV]]'', ''[[yknT]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykuV]]'', ''[[yknT]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14240 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14240 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14240 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:rok_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:rok_context.gif]] | ||
Revision as of 12:42, 13 May 2013
- Description: repressor of comK, nucleoid associated protein that serves to help repress expression of A+T-rich genes, many of which appear to have been acquired by horizontal gene transfer
| Gene name | rok |
| Synonyms | ykuW |
| Essential | no |
| Product | transcriptional repressor |
| Function | regulation of genetic competence |
| Gene expression levels in SubtiExpress: rok | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 21 kDa, 9.701 |
| Gene length, protein length | 573 bp, 191 aa |
| Immediate neighbours | ykuV, yknT |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
genetic competence, transcription factors and their control
This gene is a member of the following regulons
AbrB regulon, Rok regulon, SinR regulon, Spo0A regulon
The Rok regulon
The gene
Basic information
- Locus tag: BSU14240
Phenotypes of a mutant
higher excision rate of the conjugative transposon ICEBs1 PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to extended regions of the B. subtilis genome that are characterized by a high A+T content and are known or believed to have been acquired by horizontal gene transfer PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34857
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rok PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
Additional publications: PubMed
