Difference between revisions of "PadR"

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* '''Description:''' repressor of ''[[yveF]]-[[yveG]]-[[padC]]'', induction occurs by binding of phenolic acids,stress response <br/><br/>
 
 
 
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Revision as of 10:30, 13 August 2012

  • Description: repressor of yveF-yveG-padC, induction occurs by binding of phenolic acids,stress response

Gene name padR
Synonyms yfiO
Essential no
Product transcriptional repressor
Function regulation of the phenolic acid stress response
Gene expression levels in SubtiExpress: padR
MW, pI 21 kDa, 7.231
Gene length, protein length 546 bp, 182 aa
Immediate neighbours yfiN, lipB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PadR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PadR expression.png
























Categories containing this gene/protein

transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

The PadR regulon:

The gene

Basic information

  • Locus tag: BSU08340

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: phenolic acid acts as molecular inducer and releases PadR from the yveF-yveG-padC promoter PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: padR (according to DBTBS)
  • Sigma factor:
  • Regulation: weak constitutive expression
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References