Difference between revisions of "Alr"
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|style="background:#ABCDEF;" align="center"|'''Function''' || peptidoglycan biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || peptidoglycan biosynthesis | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU04640 alr] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 8.431 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 8.431 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydcC]]'', ''[[ndoAI]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydcC]]'', ''[[ndoAI]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU04640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU04640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU04640 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:alr_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:alr_context.gif]] | ||
Revision as of 12:11, 13 May 2013
| Gene name | alr |
| Synonyms | dal, alrA |
| Essential | yes PubMed |
| Product | alanine racemase |
| Function | peptidoglycan biosynthesis |
| Gene expression levels in SubtiExpress: alr | |
| MW, pI | 43 kDa, 8.431 |
| Gene length, protein length | 1167 bp, 389 aa |
| Immediate neighbours | ydcC, ndoAI |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04640
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-alanine = D-alanine (according to Swiss-Prot)
- Protein family: alanine racemase family (according to Swiss-Prot)
- Paralogous protein(s): YncD
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1L6G (with N-[5�-phosphopyridoxyl]-D-alanine, Geobacillus stearothermophilus), 1SFT (Geobacillus stearothermophilus)
- UniProt: P10725
- KEGG entry: [2]
- E.C. number: 5.1.1.1
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
M P Heaton, R B Johnston, T L Thompson
Controlled lysis of bacterial cells utilizing mutants with defective synthesis of D-alanine.
Can J Microbiol: 1988, 34(3);256-61
[PubMed:3138014]
[WorldCat.org]
[DOI]
(P p)
