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** suppressor of ''[[recU]]'' mutations, participates in the stabilization and or processing of holliday junction intermediates {{PubMed|11810266}}<br/> | ** suppressor of ''[[recU]]'' mutations, participates in the stabilization and or processing of holliday junction intermediates {{PubMed|11810266}}<br/> | ||
** alternative description: antagonist to [[SigF]], required for the switch from [[SigF]]- to [[SigG]]-dependent gene expression in the forespore {{PubMed|21037003}}<br/><br/> | ** alternative description: antagonist to [[SigF]], required for the switch from [[SigF]]- to [[SigG]]-dependent gene expression in the forespore {{PubMed|21037003}}<br/><br/> | ||
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|style="background:#ABCDEF;" align="center"|'''Function''' || homologous recombination | |style="background:#ABCDEF;" align="center"|'''Function''' || homologous recombination | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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* '''Operon:''' | * '''Operon:''' | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigF]] {{PubMed|21037003}}, [[SigG]] {{PubMed|21037003}} |
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* '''Regulation:''' expressed in two waves in the forespore (after two hours ([[SigF]]) and three hours ([[SigG]]) after the onset of sporulation) {{PubMed|21037003}} | * '''Regulation:''' expressed in two waves in the forespore (after two hours ([[SigF]]) and three hours ([[SigG]]) after the onset of sporulation) {{PubMed|21037003}} | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 10:14, 7 August 2012
- Description:
| Gene name | subA |
| Synonyms | yabK |
| Essential | no |
| Product | unknown |
| Function | homologous recombination |
| MW, pI | 8 kDa, 5.192 |
| Gene length, protein length | 228 bp, 76 aa |
| Immediate neighbours | spoVC, mfd |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
DNA repair/ recombination, sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00540
Phenotypes of a mutant
sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: localizes diffusely within the forespore compartment of sporangia at both early and late stages of sporulation, cytosolic protein PubMed
Database entries
- Structure:
- UniProt: P37553
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation: expressed in two waves in the forespore (after two hours (SigF) and three hours (SigG) after the onset of sporulation) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Begoña Carrasco, M Castillo Cozar, Rudi Lurz, Juan C Alonso, Silvia Ayora
Genetic recombination in Bacillus subtilis 168: contribution of Holliday junction processing functions in chromosome segregation.
J Bacteriol: 2004, 186(17);5557-66
[PubMed:15317759]
[WorldCat.org]
[DOI]
(P p)
B Carrasco, S Fernández, K Asai, N Ogasawara, J C Alonso
Effect of the recU suppressors sms and subA on DNA repair and homologous recombination in Bacillus subtilis.
Mol Genet Genomics: 2002, 266(5);899-906
[PubMed:11810266]
[WorldCat.org]
[DOI]
(P p)
Additional publications: PubMed
