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<big>'''Paper of the month: March 2012'''</big>  
 
<big>'''Paper of the month: March 2012'''</big>  
* [http://www.ncbi.nlm.nih.gov/pubmed/22333917 Beckmann ''et al''.] from the lab of [[Roland Hartmann]] show how [[bsrA|6S RNA]] is released from [[RNA polymerase]] upon interaction with short 'product' RNAs (pRNAs) that are formed as a product of the interaction between [[SigA]]-containing [[RNA polymerase]] and [[bsrA|6S RNA]].
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* [http://www.ncbi.nlm.nih.gov/pubmed/22383848 Buescher ''et al''.] and [http://www.ncbi.nlm.nih.gov/pubmed/22383849 Nicholas ''et al''.] from the BaSysBio consortium diected by [[Philippe Noirot]] studied the dynamic metabolic and transcriptional responses of ''B. subtilis'' to changes of the growth conditions. One of the major issues is the adaptation of the cells upon a nutrient switch from glucose to malate and ''vice versa''. Importantly, the study by [http://www.ncbi.nlm.nih.gov/pubmed/22383849 Nicholas ''et al''.] provides an analysis of gene expression at 104 different conditions as revealed by tiling arrays.
* '''Relevant ''Subti''Wiki pages:'''  [[Roland Hartmann]], [[bsrA|6S RNA]], [[SigA]], [[RNA polymerase]], [[transcription]]
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* '''Relevant ''Subti''Wiki pages:'''  [[Philippe Noirot]], [[Michael Hecker]], [[Uwe Völker]], [[Philippe Bessières]], [[Uwe Sauer]], [[Stephane Aymerich]], [[Tony Wilkinson]], [[metabolism]], [[transcription]], [[CcpA]], [[Sigma factors]], [[ncRNA|sRNAs]], [[Rho]]
''Beckmann BM, Hoch PG, Marz M, Willkomm DK, Salas M, Hartmann RK''
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<pubmed>22383848 22383849</pubmed>
'''A pRNA-induced structural rearrangement triggers 6S-1 RNA release from RNA polymerase in ''Bacillus subtilis''.'''
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* '''A comment on these papers:'''
EMBO J. 2012, Feb 14. doi: 10.1038/emboj.2012.23. [Epub ahead of print]
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<pubmed> 22383834 </pubmed>
{{PubMed|22333917}}
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* [[Previous papers of the month]]
 
* [[Previous papers of the month]]
  

Revision as of 16:26, 4 March 2012

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Paper of the month: March 2012

Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849] [WorldCat.org] [DOI] (I p)

Joerg Martin Buescher, Wolfram Liebermeister, Matthieu Jules, Markus Uhr, Jan Muntel, Eric Botella, Bernd Hessling, Roelco Jacobus Kleijn, Ludovic Le Chat, François Lecointe, Ulrike Mäder, Pierre Nicolas, Sjouke Piersma, Frank Rügheimer, Dörte Becher, Philippe Bessieres, Elena Bidnenko, Emma L Denham, Etienne Dervyn, Kevin M Devine, Geoff Doherty, Samuel Drulhe, Liza Felicori, Mark J Fogg, Anne Goelzer, Annette Hansen, Colin R Harwood, Michael Hecker, Sebastian Hubner, Claus Hultschig, Hanne Jarmer, Edda Klipp, Aurélie Leduc, Peter Lewis, Frank Molina, Philippe Noirot, Sabine Peres, Nathalie Pigeonneau, Susanne Pohl, Simon Rasmussen, Bernd Rinn, Marc Schaffer, Julian Schnidder, Benno Schwikowski, Jan Maarten Van Dijl, Patrick Veiga, Sean Walsh, Anthony J Wilkinson, Jörg Stelling, Stéphane Aymerich, Uwe Sauer
Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism.
Science: 2012, 335(6072);1099-103
[PubMed:22383848] [WorldCat.org] [DOI] (I p)

  • A comment on these papers:

Guilhem Chalancon, Kai Kruse, M Madan Babu
Cell biology. Reconfiguring regulation.
Science: 2012, 335(6072);1050-1
[PubMed:22383834] [WorldCat.org] [DOI] (I p)



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