Difference between revisions of "PdaC"
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cotT]]'', ''[[yjfA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cotT]]'', ''[[yjfA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12100 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yjeA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yjeA_context.gif]] | ||
Revision as of 12:35, 13 May 2013
- Description: peptidoglycan deacetylase C
| Gene name | yjeA |
| Synonyms | |
| Essential | no |
| Product | polysaccharide deacetylase C |
| Function | cell wall modification |
| MW, pI | 53 kDa, 9.105 |
| Gene length, protein length | 1401 bp, 467 aa |
| Immediate neighbours | cotT, yjfA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU12100
Phenotypes of a mutant
- sensitive to lysozyme treatment PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- deacetylates N-acetylmuramic acid (MurNAc) but not GlcNAc from peptidoglycan PubMed
- Protein family: polysaccharide deacetylase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- K(m)=4.8 mM and k(cat)=0.32 s(-1) (toward B. subtilis peptidoglycan) PubMed
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O34798
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kaori Kobayashi, I Putu Sudiarta, Takeko Kodama, Tatsuya Fukushima, Katsutoshi Ara, Katsuya Ozaki, Junichi Sekiguchi
Identification and characterization of a novel polysaccharide deacetylase C (PdaC) from Bacillus subtilis.
J Biol Chem: 2012, 287(13);9765-9776
[PubMed:22277649]
[WorldCat.org]
[DOI]
(I p)
Ka-Lun Ng, Chui-Chi Lam, Zhibiao Fu, Yi-Fan Han, Karl W K Tsim, Wan-Keung R Wong
Cloning and characterization of the yjeA gene, encoding a novel deoxyribonuclease, from Bacillus subtilis.
J Biochem: 2007, 142(5);647-54
[PubMed:17878218]
[WorldCat.org]
[DOI]
(P p)
Paola Bisicchia, David Noone, Efthimia Lioliou, Alistair Howell, Sarah Quigley, Thomas Jensen, Hanne Jarmer, Kevin M Devine
The essential YycFG two-component system controls cell wall metabolism in Bacillus subtilis.
Mol Microbiol: 2007, 65(1);180-200
[PubMed:17581128]
[WorldCat.org]
[DOI]
(P p)
