SpoIIQ

• Description: component of the SpoIIIAH-SpoIIQ type III secretion system residing in the forespore membrane, required for anchoring of proteins on both sides of the sporulation septum
  
  

Gene name	spoIIQ
Synonyms	ywnI
Essential	no
Product	component of a type III secretion system
Function	forespore engulfment
Interactions involving this protein in SubtInteract: SpoIIQ
MW, pI	30 kDa, 4.475
Gene length, protein length	849 bp, 283 aa
Immediate neighbours	ywnJ, ywnH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigF regulon

The gene

Basic information

• Locus tag: BSU36550

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SpoIIIAH(12)-SpoIIQ(12) (interaction between proteins membrane proteins expressed in the mother cell and the forespore, respectively; the complex forms a 60 Å channel made up of twelve subunits of each protein) PubMed
  • SpoIIQ-SpoIIE

• Localization:
  • forespore membrane (according to Swiss-Prot)

Database entries

• Structure:
  • 3UZO; 3TUF (the SpoIIQ-SpoIIIAH pore forming complex) PubMed

• UniProt: P71044

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoIIQ PubMed

• Sigma factor: SigF PubMed

• Regulation:
  • expressed early during sporulation in the forespore (SigF) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed