BrnQ

• Description: branched-chain amino acid transporter
  
  

Gene name	brnQ
Synonyms	yrdJ
Essential	no
Product	branched-chain amino acid transporter
Function	uptake of branched-chain amino acids
Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis, Ile, Leu, Val
MW, pI	46 kDa, 9.777
Gene length, protein length	1320 bp, 440 aa
Immediate neighbours	yrdK, azlD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of amino acids, utilization of amino acids

This gene is a member of the following regulons

AzlB regulon

The gene

Basic information

• Locus tag: BSU26690

Expression

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: branched chain amino acid transporter family (according to Swiss-Prot)

• Paralogous protein(s): BraB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P94499

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: azlB-azlC-azlD-brnQ-yrdK PubMed

• Sigma factor:

• Regulation: repressed by AzlB PubMed

• Regulatory mechanism: AzlB: transcriptional repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

B R Belitsky, M C Gustafsson, A L Sonenshein, C Von Wachenfeldt
An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport.
J Bacteriol: 1997, 179(17);5448-57
[PubMed:9287000] [WorldCat.org] [DOI] (P p)