YjcD

• Description: similar to ATP-dependent DNA helicase
  
  

Gene name	yjcD
Synonyms
Essential	no
Product	unknown
Function	unknown
Metabolic function and regulation of this protein in SubtiPathways: Folate
MW, pI	86 kDa, 8.015
Gene length, protein length	2277 bp, 759 aa
Immediate neighbours	spoVIF, yjzE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

DNA repair/ recombination

The gene

Basic information

• Locus tag: BSU11820

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: uvrD-like helicase C-terminal domain (according to Swiss-Prot)

• Paralogous protein(s): PcrA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure:
  • 2PJR (PcrA product complex, complex with sulphate ion, Geobacillus stearothermophilus, 36% identity, 55% similarity)
  • 1PJR (PcrA substrate complex, complex with DNA, Geobacillus stearothermophilus, 36% identity, 55% similarity)

• UniProt: O31626

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

S S Velankar, P Soultanas, M S Dillingham, H S Subramanya, D B Wigley
Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism.
Cell: 1999, 97(1);75-84
[PubMed:10199404] [WorldCat.org] [DOI] (P p)