Difference between revisions of "PonA"
(→References) |
(→Extended information on the protein) |
||
Line 86: | Line 86: | ||
* '''Localization:''' | * '''Localization:''' | ||
** membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed] | ** membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed] | ||
− | ** localizes to the spore septum during sporulation {{PubMed|15758244}}, this depends on [[YvcK]] {{PubMed|21320184}} | + | ** localizes to the spore septum during sporulation {{PubMed|15758244,15262952}} |
+ | ** localizes to the vegetative septum {{PubMed|15262952}}, this depends on [[YvcK]] {{PubMed|21320184}} | ||
=== Database entries === | === Database entries === |
Revision as of 17:30, 15 July 2011
- Description: penicillin-binding protein 1A/1B
Gene name | ponA |
Synonyms | |
Essential | no |
Product | penicillin-binding protein 1A/1B |
Function | bifunctional glucosyltransferase/ transpeptidase |
MW, pI | 99 kDa, 4.752 |
Gene length, protein length | 2742 bp, 914 aa |
Immediate neighbours | recU, ypoC |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
cell wall synthesis, cell envelope stress proteins (controlled by SigM, W, X, Y), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22320
Phenotypes of a mutant
prevents bulging of the cells when grown at low Mg(2+) concentrations, suppresses the lethal effect of a mreB mutation PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P39793
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: constitutive during vegetative growth PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab
- Antibody:
Labs working on this gene/protein
Jeff Errington, Newcastle University, UK homepage
Your additional remarks
References
Reviews
Original publications