YvrHa

• Description: co-sigma factor (with YvrI)
  
  

Gene name	yvrHa
Synonyms	rsoA
Essential	no
Product	co-sigma factor (with YvrI)
Function	RNA polymerase sigma factor
MW, pI	9.5 kDa, 4.69
Gene length, protein length	240 bp, 79 amino acids
Immediate neighbours	yvrHb, yvrI
Gene sequence (+200bp)	Protein sequence
Genetic context

Categories containing this gene/protein

transcription, sigma factors and their control, acid stress proteins (controlled by YvrI-YvrHa)

This gene is a member of the following regulons

YvrHb regulon, YvrI-YvrHa regulon

The YvrI-YvrHa regulon

• oxdC-yvrL
• yvrI-yvrHa
• yvrJ

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: [1]

• SubtiList entry: does not exist

Additional information

The sequence of the former yvrH gene was corrected, and does now contain two genes, yvrHa and yvrHb.

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: corresponds to region 2 of a sigma factor PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YvrHa-RpoC PubMed, YvrI-YvrHa PubMed

• Localization:

Database entries

• Structure:

• UniProt: C0H3R4

• KEGG entry: no entry

• E.C. number:

Expression and regulation

• Operon: yvrI-yvrHa PubMed

• Sigma factor: YvrI-YvrHa PubMed

• Regulation: induced by acidic growth conditions PubMed

• Regulatory mechanism: activated by YvrHb PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage