Difference between revisions of "NifZ"
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| − | * '''Description:''' | + | * '''Description:''' cysteine desulfurase<br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || cysteine desulfurase |
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|style="background:#ABCDEF;" align="center"|'''Function''' || thiamine biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || thiamine biosynthesis | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Protein family:''' | * '''Protein family:''' | ||
| − | * '''Paralogous protein(s):''' [[NifS]], [[YrvO]], [[ | + | * '''Paralogous protein(s):''' [[NifS]], [[YrvO]], [[SufS]], [[YcbU]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
* '''Localization:''' | * '''Localization:''' | ||
Revision as of 09:15, 2 July 2011
- Description: cysteine desulfurase
| Gene name | nifZ |
| Synonyms | iscSB |
| Essential | no |
| Product | cysteine desulfurase |
| Function | thiamine biosynthesis |
| Metabolic function and regulation of this protein in SubtiPathways: Thiamin | |
| MW, pI | 41 kDa, 6.34 |
| Gene length, protein length | 1143 bp, 381 aa |
| Immediate neighbours | ytbJ, braB |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29590
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: O34874
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578]
[WorldCat.org]
[DOI]
(I p)
Original publications
J T Kaiser, T Clausen, G P Bourenkow, H D Bartunik, S Steinbacher, R Huber
Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
J Mol Biol: 2000, 297(2);451-64
[PubMed:10715213]
[WorldCat.org]
[DOI]
(P p)
