Difference between revisions of "ThrB"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
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=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 23:04, 8 December 2010
- Description: homoserine kinase
| Gene name | thrB |
| Synonyms | thrA |
| Essential | no |
| Product | homoserine kinase |
| Function | biosynthesis of threonine |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 33 kDa, 4.735 |
| Gene length, protein length | 927 bp, 309 aa |
| Immediate neighbours | yuxL, thrC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU32240
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-homoserine = ADP + O-phospho-L-homoserine (according to Swiss-Prot)
- Protein family: Homoserine kinase subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 3HUL (from Listeria monocytogenes, 41% identity, 61% similarity)
- UniProt: P04948
- KEGG entry: [2]
- E.C. number: 2.7.1.39
Additional information
Expression and regulation
- Regulation: repressed by casamino acids PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
