Difference between revisions of "SpoIVFB"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[sigma factors and their control]]}}, | ||
| + | {{SubtiWiki category|[[sporulation proteins]]}}, | ||
| + | {{SubtiWiki category|[[membrane proteins]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[SigE regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 21:59, 8 December 2010
- Description: intramembrane metalloprotease, processing of pro-sigma-K to active SigK
| Gene name | spoIVFB |
| Synonyms | |
| Essential | no |
| Product | intramembrane metalloprotease |
| Function | processing of pro-sigma-K to active SigK |
| MW, pI | 33 kDa, 8.483 |
| Gene length, protein length | 864 bp, 288 aa |
| Immediate neighbours | rplU, spoIVFA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
sigma factors and their control, sporulation proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27970
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: peptidase M50B family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- C-terminal cystathionine-beta-synthase (CBS) domain, this domain binds ATP PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity: ATP regulates substrate access to the active site and renders cleavage sensitive to the cellular energy level PubMed
- Localization: cell membrane
Database entries
- Structure:
- UniProt: P26937
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Gu Chen, Xu Zhang
New insights into S2P signaling cascades: regulation, variation, and conservation.
Protein Sci: 2010, 19(11);2015-30
[PubMed:20836086]
[WorldCat.org]
[DOI]
(I p)
Original Publications
