Difference between revisions of "SpoIISA"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[sporulation proteins]]}}, | ||
| + | {{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}}, | ||
| + | {{SubtiWiki category|[[membrane proteins]]}} | ||
| + | |||
| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[SigK regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 18:48, 8 December 2010
- Description: lethal when synthesized during vegetative growth in the absence of SpoIISB
| Gene name | spoIISA |
| Synonyms | ykaC |
| Essential | no |
| Product | toxin |
| Function | programmed cell death |
| MW, pI | 28 kDa, 4.683 |
| Gene length, protein length | 744 bp, 248 aa |
| Immediate neighbours | spoIISB, pit |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
sporulation proteins, toxins, antitoxins and immunity against toxins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU12830
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: O34853
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- levels increase at the point of entry into stationary phase of cell cultures grown in sporulation-inducing medium, this is independent of Spo0A PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Patrik Florek, Katarína Muchová, Pamela Pavelcíková, Imrich Barák
Expression of functional Bacillus SpoIISAB toxin-antitoxin modules in Escherichia coli.
FEMS Microbiol Lett: 2008, 278(2);177-84
[PubMed:18096016]
[WorldCat.org]
[DOI]
(P p)
Additional Publications: PubMed
