|
|
| Line 1: |
Line 1: |
| | + | |
| | {{CategoryTree | | {{CategoryTree |
| | |Parents= | | |Parents= |
| − | * 1. [[Cellular processes]] | + | * 4. [[Lifestyles]] |
| − | ** 1.2. [[Transporters]] | + | ** 4.2. [[Sporulation and Germination]] |
| | |Neighbours= | | |Neighbours= |
| − | * 1.2.1. [[ABC transporters]] | + | * 4.2.1. [[Sporulation proteins]] |
| − | * 1.2.2. [[Phosphotransferase systems]] | + | * 4.2.2. [[Phosphorelay]] |
| − | * 1.2.3. [[Transporters/ other]] | + | * 4.2.3. [[Sporulation/ other]] |
| | + | * 4.2.4. [[Germination]] |
| | |Related= | | |Related= |
| − | * [[PRD-containing transcription factors]]
| + | none |
| − | * [[transport proteins]]
| |
| − | * [[trigger enzymes]]
| |
| | |}} | | |}} |
| − |
| |
| − | __TOC__
| |
| − | <br><br>
| |
| − | =The PEP:Sugar Phosphotransferase System=
| |
| − |
| |
| − | '''The PTS is a sugar transport system that couples the transport of a sugar to its phosphorylation. The phosphate group is derived from phosphoenolpyruvate (PEP) and transferred via the general PTS proteins [[ptsI|Enzyme I]] ([[ptsI|EI]]) and [[ptsH|HPr]] to the substrate-specific Enzymes II (EII) to the incoming sugars.'''
| |
| − |
| |
| − | '''In addition to its role in sugar transport, the PTS is also involved in the regulation of carbon metabolism.'''
| |
| − |
| |
| − | ==General PTS proteins==
| |
| − | * [[ptsI|Enzyme I]]
| |
| − | * [[ptsH|HPr]]
| |
| − |
| |
| − | ==Sugar specific PTS proteins==
| |
| − | * [[PtsG]]: glucose permease, EIICBA
| |
| − | * [[GamP]]: glucosamine permease, EIICBA
| |
| − | * [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
| |
| − | * [[MtlA]], [[MtlF]]: mannitol permease
| |
| − | * [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease
| |
| − | * [[TreP]]: trehalose permease
| |
| − | * [[MalP]]: maltose permease
| |
| − | * [[FruA]]: fructose permease
| |
| − | * [[ManP]]: mannose permease
| |
| − | * [[NagP]]: N-acetylglucosamine permease, EIICB component
| |
| − | * [[LevD]], [[LevE]], [[LevF]], [[LevG]]: fructose permease
| |
| − | * [[SacP]]: sucrose permease (high affinity)
| |
| − | * [[SacY]]: sucrose permease (low affinity)
| |
| − | * [[LicA]], [[LicB]], [[LicC]]: lichenan permease
| |
| − | * [[BglP]]: ß-glucoside permease
| |
| − | * [[YpqE]]: unknown EIIA component
| |
| − | * [[YwbA]]: unknown EIIC component
| |
| − | * [[YyzE]]: unknown PTS protein
| |
| − |
| |
| − | ==Proteins closely related to the PTS==
| |
| − | * [[Crh]]: [[ptsH|HPr]]-like protein with exculsively regulatory functions (His-15 is not conserved
| |
| − | * [[HprK]]: [[ptsH|HPr]]-kinase, key factor for carbon catabolite repression
| |
| − |
| |
| − | ==Non-PTS proteins controlled by PTS-dependent phosphorylation==
| |
| − | * [[PRD-containing transcription factors]]
| |
| − | * [[GlpK]]
| |
| − |
| |
| − | ==The PTS in [[SubtiPathways|''Subti''Pathways]]==
| |
| − | * [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]
| |
| − | * [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]
| |
| − |
| |
| − | ==Relevant Reviews==
| |
| − | <pubmed>17158705 9871918 9663674 10627040 11532441 16339738 </pubmed>
| |
| | | | |
| | == Genes in this functional category == | | == Genes in this functional category == |
| − | * [[bglP]] | + | * [[disA]] |
| − | * [[fruA]] | + | * [[floT]] |
| − | * [[gamP]] | + | * [[jag]] |
| − | * [[gmuA]] | + | * [[soj]] |
| − | * [[gmuB]] | + | * [[spo0J]] |
| − | * [[gmuC]] | + | * [[spo0M]] |
| − | * [[levD]] | + | * [[spoIIB]] |
| − | * [[levE]] | + | * [[spoIIGA]] |
| − | * [[levF]] | + | * [[spoIIIE]] |
| − | * [[levG]] | + | * [[spoIIIJ]] |
| − | * [[licA]] | + | * [[spoIISB]] |
| − | * [[licB]] | + | * [[spoVG]] |
| − | * [[licC]] | + | * [[spoVS]] |
| − | * [[malP]] | + | * [[surC]] |
| − | * [[manP]] | + | * [[ywcE]] |
| − | * [[mtlA]]
| |
| − | * [[mtlF]]
| |
| − | * [[murP]]
| |
| − | * [[nagP]]
| |
| − | * [[ptsG]]
| |
| − | * [[ptsH]]
| |
| − | * [[ptsI]]
| |
| − | * [[sacP]]
| |
| − | * [[sacX]]
| |
| − | * [[treP]]
| |
| − | * [[ypqE]]
| |
| − | * [[ywbA]]
| |
| − | * [[yyzE]]
| |
