CotY

• Description: spore coat protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat
  
  

Gene name	cotY
Synonyms
Essential	no
Product	spore coat protein (insoluble fraction)
Function	spore coat assembly
MW, pI	17 kDa, 4.857
Gene length, protein length	486 bp, 162 aa
Immediate neighbours	cotZ, cotX
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU11750

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: homotypic interaction PubMed, CotY-CotZ PubMed

• Localization: spore wall (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q08311

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotY-cotZ PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism:
  • GerE: transcription activation PubMed
  • GerR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: