Difference between revisions of "RpoA"
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| − | * '''Description:''' RNA polymerase alpha subunit <br/><br/> | + | * '''Description:''' [[RNA polymerase]] alpha subunit <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || RNA polymerase alpha subunit | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[RNA polymerase]] alpha subunit |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || transcription | |style="background:#ABCDEF;" align="center"|'''Function''' || transcription | ||
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* '''Catalyzed reaction/ biological activity:''' Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot) | * '''Catalyzed reaction/ biological activity:''' Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot) | ||
| − | * '''Protein family:''' RNA polymerase alpha chain family (according to Swiss-Prot) | + | * '''Protein family:''' [[RNA polymerase]] alpha chain family (according to Swiss-Prot) |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[ | + | * '''Interactions:''' |
| + | ** [[RpoA]]-[[RpoB]]-[[RpoC]] {{PubMed|10499798}} | ||
| + | ** [[CcpN]]-[[RpoA]] {{PubMed|19726675}}, [[RpoA]]-[[Spx]] | ||
* '''Localization:''' | * '''Localization:''' | ||
Revision as of 17:53, 21 August 2010
- Description: RNA polymerase alpha subunit
| Gene name | rpoA |
| Synonyms | |
| Essential | yes PubMed |
| Product | RNA polymerase alpha subunit |
| Function | transcription |
| MW, pI | 34 kDa, 4.593 |
| Gene length, protein length | 942 bp, 314 aa |
| Immediate neighbours | rpsK, rplQ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU01430
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot)
- Protein family: RNA polymerase alpha chain family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 1Z3E (C-terminal domain, complex with Spx)
- UniProt: P20429
- KEGG entry: [2]
- E.C. number: 2.7.7.6
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
