Difference between revisions of "FabI"
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* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
− | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' |
+ | ** inhibited by triclosan {{PubMed|11325930}} | ||
* '''Interactions:''' | * '''Interactions:''' | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
** expressed when the cells experience a lack of malonyl-CoA ([[FapR]]) {{PubMed|12737802}} | ** expressed when the cells experience a lack of malonyl-CoA ([[FapR]]) {{PubMed|12737802}} | ||
− | |||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' |
Revision as of 14:17, 14 January 2010
- Description: enoyl-acyl carrier protein reductase
Gene name | fabI |
Synonyms | yjbW |
Essential | no |
Product | enoyl-acyl carrier protein reductase |
Function | fatty acid biosynthesis |
MW, pI | 27 kDa, 5.605 |
Gene length, protein length | 774 bp, 258 aa |
Immediate neighbours | thiD, cotO |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU11720
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH (according to Swiss-Prot)
- Protein family: FabI subfamily (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- inhibited by triclosan PubMed
- Interactions:
- Localization:
Database entries
- UniProt: P54616
- KEGG entry: [3]
- E.C. number: 1.3.1.9
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications