SenS

• Description: transcriptional regulator of extracellular enzyme genes
  
  

Gene name	senS
Synonyms
Essential	no
Product	transcriptional regulator
Function	regulation of extracellular enzyme genes
MW, pI	8 kDa, 10.551
Gene length, protein length	216 bp, 72 aa
Immediate neighbours	ygaK, katA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU08810

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P21344

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: senS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Eiji Kawachi, Sadanobu Abe, Teruo Tanaka
Inhibition of Bacillus subtilis scoC expression by multicopy senS.
J Bacteriol: 2005, 187(24);8526-30
[PubMed:16321961] [WorldCat.org] [DOI] (P p)

P M McCready, R H Doi
Bacillus subtilis SenS exerts its activity through a site in the 5' flanking region of the aprE promoter.
J Gen Microbiol: 1992, 138(10);2069-74
[PubMed:1479343] [WorldCat.org] [DOI] (P p)

L F Wang, R H Doi
Complex character of senS, a novel gene regulating expression of extracellular-protein genes of Bacillus subtilis.
J Bacteriol: 1990, 172(4);1939-47
[PubMed:2108127] [WorldCat.org] [DOI] (P p)