Difference between revisions of "PhrG"
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| − | * '''Description:''' phosphatase (RapG) regulator <br/><br/> | + | * '''Description:''' phosphatase ([[RapG]]) regulator <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase (RapG) regulator | + | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase ([[RapG]]) regulator |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[DegU]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4 kDa, 9.017 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4 kDa, 9.017 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' binds to [[RapG]], this results in the inability of [[RapG]] to interact with [[DegU]] {{PubMed|12950930}} |
* '''Protein family:''' phr family (according to Swiss-Prot) | * '''Protein family:''' phr family (according to Swiss-Prot) | ||
| Line 70: | Line 70: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' [[PhrG]]-[[RapG]] {{PubMed|12950930}} |
* '''Localization:''' | * '''Localization:''' | ||
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=References= | =References= | ||
| − | <pubmed>16553878,12850135, </pubmed> | + | <pubmed>16553878,12850135, 12950930</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:12, 29 November 2009
- Description: phosphatase (RapG) regulator
| Gene name | phrG |
| Synonyms | yycL |
| Essential | no |
| Product | phosphatase (RapG) regulator |
| Function | control of DegU activity |
| MW, pI | 4 kDa, 9.017 |
| Gene length, protein length | 114 bp, 38 aa |
| Immediate neighbours | rapG, rocF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU40310
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to RapG, this results in the inability of RapG to interact with DegU PubMed
- Protein family: phr family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: O32295
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kentaro Hayashi, Tsukahara Kensuke, Kazuo Kobayashi, Naotake Ogasawara, Mitsuo Ogura
Bacillus subtilis RghR (YvaN) represses rapG and rapH, which encode inhibitors of expression of the srfA operon.
Mol Microbiol: 2006, 59(6);1714-29
[PubMed:16553878]
[WorldCat.org]
[DOI]
(P p)
Mitsuo Ogura, Kana Shimane, Kei Asai, Naotake Ogasawara, Teruo Tanaka
Binding of response regulator DegU to the aprE promoter is inhibited by RapG, which is counteracted by extracellular PhrG in Bacillus subtilis.
Mol Microbiol: 2003, 49(6);1685-97
[PubMed:12950930]
[WorldCat.org]
[DOI]
(P p)
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
