Difference between revisions of "CtaC"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | ** '''Operon:''' ''[[ctaB]]-[[ctaC]]-[[ctaD]]-[[ctaE]]-[[ctaF]]-[[ctaG]]'' {{PubMed|9829923}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| − | * '''Regulation:''' repressed by glucose (11-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | + | * '''Regulation:''' |
| − | + | ** expressed under anaerobic conditions ([[ResD]]) {{PubMed|9829923}} | |
| + | ** repressed by glucose (11-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
| − | * '''Regulatory mechanism:''' [[ | + | * '''Regulatory mechanism:''' |
| − | ** [[ | + | ** [[ResD]]: transcription activation {{PubMed|9829923}} |
| + | ** [[CcpA]]: transcription repression | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 20:20, 8 October 2009
- Description: cytochrome-c oxidase (subunit II)
| Gene name | ctaC |
| Synonyms | |
| Essential | no |
| Product | cytochrome-c oxidase (subunit II) |
| Function | respiration |
| MW, pI | 39 kDa, 8.635 |
| Gene length, protein length | 1068 bp, 356 aa |
| Immediate neighbours | ctaB, ctaD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU14890
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O (according to Swiss-Prot)
- Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P24011
- KEGG entry: [3]
- E.C. number: 1.9.3.1
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
N Azarkina, S Siletsky, V Borisov, C von Wachenfeldt, L Hederstedt, A A Konstantinov
A cytochrome bb'-type quinol oxidase in Bacillus subtilis strain 168.
J Biol Chem: 1999, 274(46);32810-7
[PubMed:10551842]
[WorldCat.org]
[DOI]
(P p)
J Bengtsson, H Tjalsma, C Rivolta, L Hederstedt
Subunit II of Bacillus subtilis cytochrome c oxidase is a lipoprotein.
J Bacteriol: 1999, 181(2);685-8
[PubMed:9882689]
[WorldCat.org]
[DOI]
(P p)
X Liu, H W Taber
Catabolite regulation of the Bacillus subtilis ctaBCDEF gene cluster.
J Bacteriol: 1998, 180(23);6154-63
[PubMed:9829923]
[WorldCat.org]
[DOI]
(P p)
J van der Oost, C von Wachenfeld, L Hederstedt, M Saraste
Bacillus subtilis cytochrome oxidase mutants: biochemical analysis and genetic evidence for two aa3-type oxidases.
Mol Microbiol: 1991, 5(8);2063-72
[PubMed:1685007]
[WorldCat.org]
[DOI]
(P p)
